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An AIF orthologue regulates apoptosis in yeast

Apoptosis-inducing factor (AIF), a key regulator of cell death, is essential for normal mammalian development and participates in pathological apoptosis. The proapoptotic nature of AIF and its mode of action are controversial. Here, we show that the yeast AIF homologue Ynr074cp controls yeast apopto...

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Detalles Bibliográficos
Autores principales: Wissing, Silke, Ludovico, Paula, Herker, Eva, Büttner, Sabrina, Engelhardt, Silvia M., Decker, Thorsten, Link, Alexander, Proksch, Astrid, Rodrigues, Fernando, Corte-Real, Manuela, Fröhlich, Kai-Uwe, Manns, Joachim, Candé, Céline, Sigrist, Stephan J., Kroemer, Guido, Madeo, Frank
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172025/
https://www.ncbi.nlm.nih.gov/pubmed/15381687
http://dx.doi.org/10.1083/jcb.200404138