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An AIF orthologue regulates apoptosis in yeast
Apoptosis-inducing factor (AIF), a key regulator of cell death, is essential for normal mammalian development and participates in pathological apoptosis. The proapoptotic nature of AIF and its mode of action are controversial. Here, we show that the yeast AIF homologue Ynr074cp controls yeast apopto...
Autores principales: | Wissing, Silke, Ludovico, Paula, Herker, Eva, Büttner, Sabrina, Engelhardt, Silvia M., Decker, Thorsten, Link, Alexander, Proksch, Astrid, Rodrigues, Fernando, Corte-Real, Manuela, Fröhlich, Kai-Uwe, Manns, Joachim, Candé, Céline, Sigrist, Stephan J., Kroemer, Guido, Madeo, Frank |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172025/ https://www.ncbi.nlm.nih.gov/pubmed/15381687 http://dx.doi.org/10.1083/jcb.200404138 |
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