Autocrine CSF-1R activation promotes Src-dependent disruption of mammary epithelial architecture

Elevated coexpression of colony-stimulating factor receptor (CSF-1R) and its ligand, CSF-1, correlates with invasiveness and poor prognosis of a variety of epithelial tumors (Kacinski, B.M. 1995. Ann. Med. 27:79–85). Apart from recruitment of macrophages to the tumor site, the mechanisms by which CS...

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Detalles Bibliográficos
Autores principales: Wrobel, Carolyn N., Debnath, Jayanta, Lin, Eva, Beausoleil, Sean, Roussel, Martine F., Brugge, Joan S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172030/
https://www.ncbi.nlm.nih.gov/pubmed/15117969
http://dx.doi.org/10.1083/jcb.200309102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172030/
https://www.ncbi.nlm.nih.gov/pubmed/15117969
http://dx.doi.org/10.1083/jcb.200309102

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