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Rab13 regulates PKA signaling during tight junction assembly

The GTPase Rab13 regulates the assembly of functional epithelial tight junctions (TJs) through a yet unknown mechanism. Here, we show that expression of the GTP-bound form of Rab13 inhibits PKA-dependent phosphorylation and TJ recruitment of the vasodilator-stimulated phosphoprotein, an actin remode...

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Detalles Bibliográficos
Autores principales: Köhler, Katja, Louvard, Daniel, Zahraoui, Ahmed
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172036/
https://www.ncbi.nlm.nih.gov/pubmed/15096524
http://dx.doi.org/10.1083/jcb.200312118