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Characterization of a hypercontraction-induced myopathy in Drosophila caused by mutations in Mhc

The Myosin heavy chain (Mhc) locus encodes the muscle-specific motor mediating contraction in Drosophila. In a screen for temperature-sensitive behavioral mutants, we have identified two dominant Mhc alleles that lead to a hypercontraction-induced myopathy. These mutants are caused by single point m...

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Detalles Bibliográficos
Autores principales: Montana, Enrico S., Littleton, J. Troy
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172052/
https://www.ncbi.nlm.nih.gov/pubmed/15051736
http://dx.doi.org/10.1083/jcb.200308158