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PKCα mediates TGFβ-induced growth inhibition of human keratinocytes via phosphorylation of S100C/A11

Growth regulation of epithelial cells is of major concern because most human cancers arise from them. We demonstrated previously a novel signal pathway involving S100C/A11 for high Ca(2+)-induced growth inhibition of normal human keratinocytes (Sakaguchi, M., M. Miyazaki, M. Takaishi, Y. Sakaguchi,...

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Detalles Bibliográficos
Autores principales: Sakaguchi, Masakiyo, Miyazaki, Masahiro, Sonegawa, Hiroyuki, Kashiwagi, Mariko, Ohba, Motoi, Kuroki, Toshio, Namba, Masayoshi, Huh, Nam-ho
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172059/
https://www.ncbi.nlm.nih.gov/pubmed/15051732
http://dx.doi.org/10.1083/jcb.200312041