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RanGAP1*SUMO1 is phosphorylated at the onset of mitosis and remains associated with RanBP2 upon NPC disassembly

The RanGTPase activating protein RanGAP1 has essential functions in both nucleocytoplasmic transport and mitosis. In interphase, a significant fraction of vertebrate SUMO1-modified RanGAP1 forms a stable complex with the nucleoporin RanBP2/Nup358 at nuclear pore complexes. RanBP2 not only acts in th...

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Detalles Bibliográficos
Autores principales: Swaminathan, Sowmya, Kiendl, Florian, Körner, Roman, Lupetti, Raffaella, Hengst, Ludger, Melchior, Frauke
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172064/
https://www.ncbi.nlm.nih.gov/pubmed/15037602
http://dx.doi.org/10.1083/jcb.200309126