Cargando…

RanGAP1*SUMO1 is phosphorylated at the onset of mitosis and remains associated with RanBP2 upon NPC disassembly

The RanGTPase activating protein RanGAP1 has essential functions in both nucleocytoplasmic transport and mitosis. In interphase, a significant fraction of vertebrate SUMO1-modified RanGAP1 forms a stable complex with the nucleoporin RanBP2/Nup358 at nuclear pore complexes. RanBP2 not only acts in th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Swaminathan, Sowmya, Kiendl, Florian, Körner, Roman, Lupetti, Raffaella, Hengst, Ludger, Melchior, Frauke
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2004
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172064/ https://www.ncbi.nlm.nih.gov/pubmed/15037602 http://dx.doi.org/10.1083/jcb.200309126

Ejemplares similares

The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes
por: Ritterhoff, Tobias, et al.
Publicado: (2016)

T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1
por: He, Yujiao, et al.
Publicado: (2021)

Molecular Characterization of the SUMO-1 Modification of RanGAP1 and Its Role in Nuclear Envelope Association
por: Mahajan, Rohit, et al.
Publicado: (1998)

Determinants of Small Ubiquitin-like Modifier 1 (SUMO1) Protein Specificity, E3 Ligase, and SUMO-RanGAP1 Binding Activities of Nucleoporin RanBP2
por: Gareau, Jaclyn R., et al.
Publicado: (2012)

SUMO-1 targets RanGAP1 to kinetochores and mitotic spindles
por: Joseph, Jomon, et al.
Publicado: (2002)

SUMO-1 Modification and Its Role in Targeting the Ran GTPase-activating Protein, RanGAP1, to the Nuclear Pore Complex
por: Matunis, Michael J., et al.
Publicado: (1998)

SUMOylation mediates the disassembly of the Smad4 nuclear export complex via RanGAP1 in KELOIDS
por: Lin, Xiaohu, et al.
Publicado: (2023)

The Ran GTPase-Activating Protein (RanGAP1) Is Critically Involved in Smooth Muscle Cell Differentiation, Proliferation and Migration following Vascular Injury: Implications for Neointima Formation and Restenosis
por: Vorpahl, Marc, et al.
Publicado: (2014)

RanBP1 stabilizes the interaction of Ran with p97 nuclear protein import
Publicado: (1996)

RanBP9 at the intersection between cofilin and Aβ pathologies: rescue of neurodegenerative changes by RanBP9 reduction
por: Woo, J A, et al.
Publicado: (2015)

RanBP2 Modulates Cox11 and Hexokinase I Activities and Haploinsufficiency of RanBP2 Causes Deficits in Glucose Metabolism
por: Aslanukov, Azamat, et al.
Publicado: (2006)

A nuclear export signal is essential for the cytosolic localization of the Ran binding protein, RanBP1
Publicado: (1996)

Insights into the Function of the CRM1 Cofactor RanBP3 from the Structure of Its Ran-Binding Domain
por: Langer, Karla, et al.
Publicado: (2011)

RanBP1 controls the Ran pathway in mammalian cells through regulation of mitotic RCC1 dynamics
por: Yau, Ka Chun, et al.
Publicado: (2020)

Ran’s downhill slide during mitosis
por: Leslie, Mitch
Publicado: (2013)

The Ran Pathway in Drosophila melanogaster Mitosis
por: Chen, Jack W. C., et al.
Publicado: (2015)

RanBP2 stops importin-β from running away
por: Leslie, Mitch
Publicado: (2011)

Workshop on RanBP2/Nup358 and acute necrotizing encephalopathy
por: Palazzo, Alexander F., et al.
Publicado: (2022)

RanBP9 controls the oligomeric state of CTLH complex assemblies
por: van gen Hassend, Pia Maria, et al.
Publicado: (2023)

Ran-dependent docking of importin-β to RanBP2/Nup358 filaments is essential for protein import and cell viability
por: Hamada, Masakazu, et al.
Publicado: (2011)

A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex
Publicado: (1996)

Novel plant SUN–KASH bridges are involved in RanGAP anchoring and nuclear shape determination
por: Zhou, Xiao, et al.
Publicado: (2012)

Ran Binding Protein 9 (RanBP9) is a novel mediator of cellular DNA damage response in lung cancer cells
por: Palmieri, Dario, et al.
Publicado: (2016)

Cooperative role of RanBP9 and P73 in mitochondria-mediated apoptosis
por: Liu, T, et al.
Publicado: (2013)

CD147 supports paclitaxel resistance via interacting with RanBP1
por: Nan, Gang, et al.
Publicado: (2022)

Nicotiana benthamiana RanBP1-1 Is Involved in the Induction of Disease Resistance via Regulation of Nuclear-Cytoplasmic Transport of Small GTPase Ran
por: Mizuno, Yuri, et al.
Publicado: (2019)

RanBPM (RanBP9) regulates mouse c-Kit receptor level and is essential for normal development of bone marrow progenitor cells
por: Puverel, Sandrine, et al.
Publicado: (2016)

The GTPase Activating Rap/RanGAP Domain-Like 1 Gene Is Associated with Chicken Reproductive Traits
por: Shen, Xu, et al.
Publicado: (2012)

The Cellular Distribution of RanGAP1 Is Regulated by CRM1-Mediated Nuclear Export in Mammalian Cells
por: Cha, Keith, et al.
Publicado: (2015)

RanBP9 Plays a Critical Role in Neonatal Brain Development in Mice
por: Palavicini, Juan Pablo, et al.
Publicado: (2013)

The association of RAN and RANBP2 gene polymerphisms with Wilms tumor risk in Chinese children
por: Huang, Xiaokai, et al.
Publicado: (2020)

RanBP2/Nup358 enhances miRNA activity by sumoylating Argonautes
por: Shen, Qingtang, et al.
Publicado: (2021)

The nucleoporin Nup50 activates the Ran guanine nucleotide exchange factor RCC1 to promote NPC assembly at the end of mitosis
por: Holzer, Guillaume, et al.
Publicado: (2021)

SGK1 affects RAN/RANBP1/RANGAP1 via SP1 to play a critical role in pre-miRNA nuclear export: a new route of epigenomic regulation
por: Dattilo, Vincenzo, et al.
Publicado: (2017)

RanBP3 enhances nuclear export of active β-catenin independently of CRM1
por: Hendriksen, Jolita, et al.
Publicado: (2005)

Species-specific vulnerability of RanBP2 shaped the evolution of SIV as it transmitted in African apes
por: Meyerson, Nicholas R., et al.
Publicado: (2018)

Exploring the suitability of RanBP2-type Zinc Fingers for RNA-binding protein design
por: De Franco, Simona, et al.
Publicado: (2019)

Distinct RanBP1 nuclear export and cargo dissociation mechanisms between fungi and animals
por: Li, Yuling, et al.
Publicado: (2019)

Role of Nesprin-2 and RanBP2 in BICD2-associated brain developmental disorders
por: Yi, Julie, et al.
Publicado: (2023)

Ran GTPase, an eukaryotic gene novelty, is involved in amphioxus mitosis
por: Coppola, Ugo, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_dl4f3f4fjthisjcqcdtp4ekvp7