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Brain development in mice lacking L1–L1 homophilic adhesion

A new mouse line has been produced in which the sixth Ig domain of the L1 cell adhesion molecule has been deleted. Despite the rather large deletion, L1 expression is preserved at normal levels. In vitro experiments showed that L1–L1 homophilic binding was lost, along with L1-α5β1 integrin binding....

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Detalles Bibliográficos
Autores principales: Itoh, Kyoko, Cheng, Ling, Kamei, Yoshimasa, Fushiki, Shinji, Kamiguchi, Hiroyuki, Gutwein, Paul, Stoeck, Alexander, Arnold, Bernd, Altevogt, Peter, Lemmon, Vance
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172083/
https://www.ncbi.nlm.nih.gov/pubmed/15067019
http://dx.doi.org/10.1083/jcb.200312107