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Role of the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptor

The cation-independent mannose 6-phosphate receptor (CI-MPR) mediates sorting of lysosomal hydrolase precursors from the TGN to endosomes. After releasing the hydrolase precursors into the endosomal lumen, the unoccupied receptor returns to the TGN for further rounds of sorting. Here, we show that t...

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Detalles Bibliográficos
Autores principales: Arighi, Cecilia N., Hartnell, Lisa M., Aguilar, Ruben C., Haft, Carol R., Bonifacino, Juan S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172094/
https://www.ncbi.nlm.nih.gov/pubmed/15078903
http://dx.doi.org/10.1083/jcb.200312055