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Transcription-dependent spatial arrangements of CFTR and adjacent genes in human cell nuclei

We investigated in different human cell types nuclear positioning and transcriptional regulation of the functionally unrelated genes GASZ, CFTR, and CORTBP2, mapping to adjacent loci on human chromosome 7q31. When inactive, GASZ, CFTR, and CORTBP2 preferentially associated with the nuclear periphery...

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Detalles Bibliográficos
Autores principales: Zink, Daniele, Amaral, Margarida D., Englmann, Andreas, Lang, Susanne, Clarke, Luka A., Rudolph, Carsten, Alt, Felix, Luther, Kathrin, Braz, Carla, Sadoni, Nicolas, Rosenecker, Joseph, Schindelhauer, Dirk
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172106/
https://www.ncbi.nlm.nih.gov/pubmed/15364959
http://dx.doi.org/10.1083/jcb.200404107