Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest

Bloom's syndrome is a rare autosomal recessive genetic disorder characterized by chromosomal aberrations, genetic instability, and cancer predisposition, all of which may be the result of abnormal signal transduction during DNA damage recognition. Here, we show that BLM is an intermediate respo...

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Detalles Bibliográficos
Autores principales: Sengupta, Sagar, Robles, Ana I., Linke, Steven P., Sinogeeva, Natasha I., Zhang, Ran, Pedeux, Remy, Ward, Irene M., Celeste, Arkady, Nussenzweig, André, Chen, Junjie, Halazonetis, Thanos D., Harris, Curtis C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172115/
https://www.ncbi.nlm.nih.gov/pubmed/15364958
http://dx.doi.org/10.1083/jcb.200405128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172115/
https://www.ncbi.nlm.nih.gov/pubmed/15364958
http://dx.doi.org/10.1083/jcb.200405128

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