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Regulation of SNAREs by tomosyn and ROCK: implication in extension and retraction of neurites

Extension of neurites requires the SNARE-dependent fusion of plasmalemmal precursor vesicles with the plasma membrane of growth cones. Here, we show that tomosyn localizes at the palm of growth cones and inhibits the fusion of the vesicles there, thus promoting transport of the vesicles to the plasm...

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Detalles Bibliográficos
Autores principales: Sakisaka, Toshiaki, Baba, Takeshi, Tanaka, Shintaro, Izumi, Genkichi, Yasumi, Masato, Takai, Yoshimi
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172130/
https://www.ncbi.nlm.nih.gov/pubmed/15240567
http://dx.doi.org/10.1083/jcb.200405002