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Organization of mammary epithelial cells into 3D acinar structures requires glucocorticoid and JNK signaling
Mammary epithelial cells cultured on a concentrated laminin-rich extracellular matrix formed 3D acinar structures that matured to polarized monolayers surrounding a lumen. In the absence of glucocorticoids mature acinus formation failed and the expression of an acinus-associated, activator protein 1...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172147/ https://www.ncbi.nlm.nih.gov/pubmed/15226308 http://dx.doi.org/10.1083/jcb.200403020 |