Mammalian PAR-1 determines epithelial lumen polarity by organizing the microtubule cytoskeleton

Epithelial differentiation involves the generation of luminal surfaces and of a noncentrosomal microtubule (MT) network aligned along the polarity axis. Columnar epithelia (e.g., kidney, intestine, and Madin-Darby canine kidney [MDCK] cells) generate apical lumina and orient MT vertically, whereas l...

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Detalles Bibliográficos
Autores principales: Cohen, David, Brennwald, Patrick J., Rodriguez-Boulan, Enrique, Müsch, Anne
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172160/
https://www.ncbi.nlm.nih.gov/pubmed/14981097
http://dx.doi.org/10.1083/jcb.200308104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172160/
https://www.ncbi.nlm.nih.gov/pubmed/14981097
http://dx.doi.org/10.1083/jcb.200308104

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