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Dendritic cell aggresome-like induced structures are dedicated areas for ubiquitination and storage of newly synthesized defective proteins

In response to inflammatory stimulation, dendritic cells (DCs) have a remarkable pattern of differentiation (maturation) that exhibits specific mechanisms to control antigen processing and presentation. One of these mechanisms is the sorting of polyubiquitinated proteins in large cytosolic aggregate...

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Detalles Bibliográficos
Autores principales: Lelouard, Hugues, Ferrand, Vincent, Marguet, Didier, Bania, Jacek, Camosseto, Voahirana, David, Alexandre, Gatti, Evelina, Pierre, Philippe
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172164/
https://www.ncbi.nlm.nih.gov/pubmed/14981091
http://dx.doi.org/10.1083/jcb.200312073