ERK activation promotes neuronal degeneration predominantly through plasma membrane damage and independently of caspase-3

Our recent studies have shown that extracellular-regulated protein kinase (ERK) promotes cell death in cerebellar granule neurons (CGN) cultured in low potassium. Here we report that the “death” phenotypes of CGN after potassium withdrawal are heterogeneous, allowing the distinction between plasma m...

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Detalles Bibliográficos
Autores principales: Subramaniam, Srinivasa, Zirrgiebel, Ute, von Bohlen und Halbach, Oliver, Strelau, Jens, Laliberté, Christine, Kaplan, David R., Unsicker, Klaus
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172179/
https://www.ncbi.nlm.nih.gov/pubmed/15123736
http://dx.doi.org/10.1083/jcb.200403028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172179/
https://www.ncbi.nlm.nih.gov/pubmed/15123736
http://dx.doi.org/10.1083/jcb.200403028

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