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ERK activation promotes neuronal degeneration predominantly through plasma membrane damage and independently of caspase-3
Our recent studies have shown that extracellular-regulated protein kinase (ERK) promotes cell death in cerebellar granule neurons (CGN) cultured in low potassium. Here we report that the “death” phenotypes of CGN after potassium withdrawal are heterogeneous, allowing the distinction between plasma m...
Autores principales: | Subramaniam, Srinivasa, Zirrgiebel, Ute, von Bohlen und Halbach, Oliver, Strelau, Jens, Laliberté, Christine, Kaplan, David R., Unsicker, Klaus |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172179/ https://www.ncbi.nlm.nih.gov/pubmed/15123736 http://dx.doi.org/10.1083/jcb.200403028 |
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