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A role for myosin-1A in the localization of a brush border disaccharidase

To gain insight regarding myosin-1A (M1A) function, we expressed a dominant negative fragment of this motor in the intestinal epithelial cell line, CACO-2(BBE). Sucrase isomaltase (SI), a transmembrane disaccharidase found in microvillar lipid rafts, was missing from the brush border (BB) in cells e...

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Detalles Bibliográficos
Autores principales: Tyska, Matthew J., Mooseker, Mark S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172191/
https://www.ncbi.nlm.nih.gov/pubmed/15138292
http://dx.doi.org/10.1083/jcb.200310031