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Radixin deficiency causes deafness associated with progressive degeneration of cochlear stereocilia

Ezrin/radixin/moesin (ERM) proteins cross-link actin filaments to plasma membranes to integrate the function of cortical layers, especially microvilli. We found that in cochlear and vestibular sensory hair cells of adult wild-type mice, radixin was specifically enriched in stereocilia, specially dev...

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Detalles Bibliográficos
Autores principales: Kitajiri, Shin-ichiro, Fukumoto, Kanehisa, Hata, Masaki, Sasaki, Hiroyuki, Katsuno, Tatsuya, Nakagawa, Takayuki, Ito, Juichi, Tsukita, Shoichiro, Tsukita, Sachiko
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172208/
https://www.ncbi.nlm.nih.gov/pubmed/15314067
http://dx.doi.org/10.1083/jcb.200402007