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Radixin deficiency causes deafness associated with progressive degeneration of cochlear stereocilia
Ezrin/radixin/moesin (ERM) proteins cross-link actin filaments to plasma membranes to integrate the function of cortical layers, especially microvilli. We found that in cochlear and vestibular sensory hair cells of adult wild-type mice, radixin was specifically enriched in stereocilia, specially dev...
Autores principales: | Kitajiri, Shin-ichiro, Fukumoto, Kanehisa, Hata, Masaki, Sasaki, Hiroyuki, Katsuno, Tatsuya, Nakagawa, Takayuki, Ito, Juichi, Tsukita, Shoichiro, Tsukita, Sachiko |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172208/ https://www.ncbi.nlm.nih.gov/pubmed/15314067 http://dx.doi.org/10.1083/jcb.200402007 |
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