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T cell receptor antagonism interferes with MHC clustering and integrin patterning during immunological synapse formation
T cell activation by nonself peptide–major histocompatibility complex (MHC) antigenic complexes can be blocked by particular sequence variants in a process termed T cell receptor antagonism. The inhibition mechanism is not understood, although such variants are encountered in viral infections and ma...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172210/ https://www.ncbi.nlm.nih.gov/pubmed/15314068 http://dx.doi.org/10.1083/jcb.200404059 |