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T cell receptor antagonism interferes with MHC clustering and integrin patterning during immunological synapse formation

T cell activation by nonself peptide–major histocompatibility complex (MHC) antigenic complexes can be blocked by particular sequence variants in a process termed T cell receptor antagonism. The inhibition mechanism is not understood, although such variants are encountered in viral infections and ma...

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Detalles Bibliográficos
Autores principales: Sumen, Cenk, Dustin, Michael L., Davis, Mark M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172210/
https://www.ncbi.nlm.nih.gov/pubmed/15314068
http://dx.doi.org/10.1083/jcb.200404059