The KinI kinesin Kif2a is required for bipolar spindle assembly through a functional relationship with MCAK

Although the microtubule-depolymerizing KinI motor Kif2a is abundantly expressed in neuronal cells, we now show it localizes to centrosomes and spindle poles during mitosis in cultured cells. RNAi-induced knockdown of Kif2a expression inhibited cell cycle progression because cells assembled monopola...

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Detalles Bibliográficos
Autores principales: Ganem, Neil J., Compton, Duane A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172212/
https://www.ncbi.nlm.nih.gov/pubmed/15302853
http://dx.doi.org/10.1083/jcb.200404012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172212/
https://www.ncbi.nlm.nih.gov/pubmed/15302853
http://dx.doi.org/10.1083/jcb.200404012

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