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The KinI kinesin Kif2a is required for bipolar spindle assembly through a functional relationship with MCAK
Although the microtubule-depolymerizing KinI motor Kif2a is abundantly expressed in neuronal cells, we now show it localizes to centrosomes and spindle poles during mitosis in cultured cells. RNAi-induced knockdown of Kif2a expression inhibited cell cycle progression because cells assembled monopola...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2004
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172212/ https://www.ncbi.nlm.nih.gov/pubmed/15302853 http://dx.doi.org/10.1083/jcb.200404012 |