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Dynamic targeting of the replication machinery to sites of DNA damage

Components of the DNA replication machinery localize into discrete subnuclear foci after DNA damage, where they play requisite functions in repair processes. Here, we find that the replication factors proliferating cell nuclear antigen (PCNA) and RPAp34 dynamically exchange at these repair foci with...

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Detalles Bibliográficos
Autores principales: Solomon, David A., Cardoso, M. Cristina, Knudsen, Erik S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172213/
https://www.ncbi.nlm.nih.gov/pubmed/15314062
http://dx.doi.org/10.1083/jcb.200312048