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Dynamic targeting of the replication machinery to sites of DNA damage
Components of the DNA replication machinery localize into discrete subnuclear foci after DNA damage, where they play requisite functions in repair processes. Here, we find that the replication factors proliferating cell nuclear antigen (PCNA) and RPAp34 dynamically exchange at these repair foci with...
Autores principales: | Solomon, David A., Cardoso, M. Cristina, Knudsen, Erik S. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172213/ https://www.ncbi.nlm.nih.gov/pubmed/15314062 http://dx.doi.org/10.1083/jcb.200312048 |
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