Raf-1 activation disrupts its binding to keratins during cell stress

Keratins 8 and 18 (K8/18) heteropolymers may regulate cell signaling via the known K18 association with 14-3-3 proteins and 14-3-3 association with Raf-1 kinase. We characterized Raf–keratin–14-3-3 associations and show that Raf associates directly with K8, independent of Raf kinase activity or Ras–...

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Detalles Bibliográficos
Autores principales: Ku, Nam-On, Fu, Haian, Omary, M. Bishr
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172217/
https://www.ncbi.nlm.nih.gov/pubmed/15314064
http://dx.doi.org/10.1083/jcb.200402051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172217/
https://www.ncbi.nlm.nih.gov/pubmed/15314064
http://dx.doi.org/10.1083/jcb.200402051

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