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Extracellular HMGB1, a signal of tissue damage, induces mesoangioblast migration and proliferation

High mobility group box 1 (HMGB1) is an abundant chromatin protein that acts as a cytokine when released in the extracellular milieu by necrotic and inflammatory cells. Here, we show that extracellular HMGB1 and its receptor for advanced glycation end products (RAGE) induce both migration and prolif...

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Detalles Bibliográficos
Autores principales: Palumbo, Roberta, Sampaolesi, Maurilio, De Marchis, Francesco, Tonlorenzi, Rossana, Colombetti, Sara, Mondino, Anna, Cossu, Giulio, Bianchi, Marco E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172232/
https://www.ncbi.nlm.nih.gov/pubmed/14744997
http://dx.doi.org/10.1083/jcb.200304135