Krox-20 inhibits Jun-NH(2)-terminal kinase/c-Jun to control Schwann cell proliferation and death

The transcription factor Krox-20 controls Schwann cell myelination. Schwann cells in Krox-20 null mice fail to myelinate, and unlike myelinating Schwann cells, continue to proliferate and are susceptible to death. We find that enforced Krox-20 expression in Schwann cells cell-autonomously inactivate...

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Detalles Bibliográficos
Autores principales: Parkinson, David B., Bhaskaran, Ambily, Droggiti, Anna, Dickinson, Sarah, D'Antonio, Maurizio, Mirsky, Rhona, Jessen, Kristjan R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172235/
https://www.ncbi.nlm.nih.gov/pubmed/14757751
http://dx.doi.org/10.1083/jcb.200307132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172235/
https://www.ncbi.nlm.nih.gov/pubmed/14757751
http://dx.doi.org/10.1083/jcb.200307132

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