Rap1 up-regulation and activation on plasma membrane regulates T cell adhesion

Rap1 and Ras are closely related GTPases that share some effectors but have distinct functions. We studied the subcellular localization of Rap1 and its sites of activation in living cells. Both GFP-tagged Rap1 and endogenous Rap1 were localized to the plasma membrane (PM) and endosomes. The PM assoc...

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Detalles Bibliográficos
Autores principales: Bivona, Trever G., Wiener, Heidi H., Ahearn, Ian M., Silletti, Joseph, Chiu, Vi K., Philips, Mark R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172240/
https://www.ncbi.nlm.nih.gov/pubmed/14757755
http://dx.doi.org/10.1083/jcb.200311093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172240/
https://www.ncbi.nlm.nih.gov/pubmed/14757755
http://dx.doi.org/10.1083/jcb.200311093

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