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Switch from αvβ5 to αvβ6 integrin expression protects squamous cell carcinomas from anoikis
Stratified squamous epithelia express the αvβ5 integrin, but in squamous cell carcinomas (SCCs) there is down-regulation of αvβ5 and up-regulation of αvβ6. To investigate the significance of this finding, we transduced an αv-negative human SCC line with retroviral vectors encoding αv integrins. αvβ5...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2004
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172256/ https://www.ncbi.nlm.nih.gov/pubmed/15289499 http://dx.doi.org/10.1083/jcb.200312074 |