Keratins modulate colonocyte electrolyte transport via protein mistargeting

The function of intestinal keratins is unknown, although keratin 8 (K8)–null mice develop colitis, hyperplasia, diarrhea, and mistarget jejunal apical markers. We quantified the diarrhea in K8-null stool and examined its physiologic basis. Isolated crypt-units from K8-null and wild-type mice have si...

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Detalles Bibliográficos
Autores principales: Toivola, Diana M., Krishnan, Selvi, Binder, Henry J., Singh, Satish K., Omary, M. Bishr
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172274/
https://www.ncbi.nlm.nih.gov/pubmed/15007064
http://dx.doi.org/10.1083/jcb.200308103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172274/
https://www.ncbi.nlm.nih.gov/pubmed/15007064
http://dx.doi.org/10.1083/jcb.200308103

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