Tumor cell α(3)β(1) integrin and vascular laminin-5 mediate pulmonary arrest and metastasis

Arrest of circulating tumor cells in distant organs is required for hematogenous metastasis, but the tumor cell surface molecules responsible have not been identified. Here, we show that the tumor cell α(3)β(1) integrin makes an important contribution to arrest in the lung and to early colony format...

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Detalles Bibliográficos
Autores principales: Wang, Hui, Fu, Weili, Im, Jae Hong, Zhou, Zengyi, Santoro, Samuel A., Iyer, Vandana, DiPersio, C. Mike, Yu, Qian-Chun, Quaranta, Vito, Al-Mehdi, Abu, Muschel, Ruth J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172296/
https://www.ncbi.nlm.nih.gov/pubmed/15024036
http://dx.doi.org/10.1083/jcb.200309112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172296/
https://www.ncbi.nlm.nih.gov/pubmed/15024036
http://dx.doi.org/10.1083/jcb.200309112

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