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Tumor cell α(3)β(1) integrin and vascular laminin-5 mediate pulmonary arrest and metastasis
Arrest of circulating tumor cells in distant organs is required for hematogenous metastasis, but the tumor cell surface molecules responsible have not been identified. Here, we show that the tumor cell α(3)β(1) integrin makes an important contribution to arrest in the lung and to early colony format...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2004
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172296/ https://www.ncbi.nlm.nih.gov/pubmed/15024036 http://dx.doi.org/10.1083/jcb.200309112 |