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Nesca, a novel adapter, translocates to the nuclear envelope and regulates neurotrophin-induced neurite outgrowth

We provide the first characterization of a novel signaling adapter, Nesca, in neurotrophic signal transduction. Nesca contains a RUN domain, a WW domain, a leucine zipper, a carboxyl-terminal SH3 domain, and several proline-rich regions. Nesca is highly expressed in the brain, is serine phosphorylat...

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Detalles Bibliográficos
Autores principales: MacDonald, James I.S., Kubu, Chris J., Meakin, Susan O.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172297/
https://www.ncbi.nlm.nih.gov/pubmed/15024033
http://dx.doi.org/10.1083/jcb.200309081