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A novel phosphatidylinositol(3,4,5)P(3) pathway in fission yeast

The mammalian tumor suppressor, phosphatase and tensin homologue deleted on chromosome 10 (PTEN), inhibits cell growth and survival by dephosphorylating phosphatidylinositol-(3,4,5)-trisphosphate (PI[3,4,5]P(3)). We have found a homologue of PTEN in the fission yeast, Schizosaccharomyces pombe (ptn1...

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Detalles Bibliográficos
Autores principales: Mitra, Prasenjit, Zhang, Yingjie, Rameh, Lucia E., Ivshina, Maria P., McCollum, Dannel, Nunnari, John J., Hendricks, Gregory M., Kerr, Monica L., Field, Seth J., Cantley, Lewis C., Ross, Alonzo H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172303/
https://www.ncbi.nlm.nih.gov/pubmed/15249580
http://dx.doi.org/10.1083/jcb.200404150