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Endocytosis of E-cadherin regulated by Rac and Cdc42 small G proteins through IQGAP1 and actin filaments

E-cadherin is a key cell–cell adhesion molecule at adherens junctions (AJs) and undergoes endocytosis when AJs are disrupted by the action of extracellular signals. To elucidate the mechanism of this endocytosis, we developed here a new cell-free assay system for this reaction using the AJ-enriched...

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Detalles Bibliográficos
Autores principales: Izumi, Genkichi, Sakisaka, Toshiaki, Baba, Takeshi, Tanaka, Shintaro, Morimoto, Koji, Takai, Yoshimi
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172308/
https://www.ncbi.nlm.nih.gov/pubmed/15263019
http://dx.doi.org/10.1083/jcb.200401078