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Endocytosis of E-cadherin regulated by Rac and Cdc42 small G proteins through IQGAP1 and actin filaments
E-cadherin is a key cell–cell adhesion molecule at adherens junctions (AJs) and undergoes endocytosis when AJs are disrupted by the action of extracellular signals. To elucidate the mechanism of this endocytosis, we developed here a new cell-free assay system for this reaction using the AJ-enriched...
Autores principales: | Izumi, Genkichi, Sakisaka, Toshiaki, Baba, Takeshi, Tanaka, Shintaro, Morimoto, Koji, Takai, Yoshimi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172308/ https://www.ncbi.nlm.nih.gov/pubmed/15263019 http://dx.doi.org/10.1083/jcb.200401078 |
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