Vav GEFs are required for β(2) integrin-dependent functions of neutrophils

Integrin regulation of neutrophils is essential for appropriate adhesion and transmigration into tissues. Vav proteins are Rho family guanine nucleotide exchange factors that become tyrosine phosphorylated in response to adhesion. Using Vav1/Vav3-deficient neutrophils (Vav1/3(ko)), we show that Vav...

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Detalles Bibliográficos
Autores principales: Gakidis, M. Angelica Martinez, Cullere, Xavier, Olson, Timothy, Wilsbacher, Julie L., Zhang, Bin, Moores, Sheri L., Ley, Klaus, Swat, Wojciech, Mayadas, Tanya, Brugge, Joan S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172310/
https://www.ncbi.nlm.nih.gov/pubmed/15249579
http://dx.doi.org/10.1083/jcb.200404166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172310/
https://www.ncbi.nlm.nih.gov/pubmed/15249579
http://dx.doi.org/10.1083/jcb.200404166

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