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Relocation of Aurora B from centromeres to the central spindle at the metaphase to anaphase transition requires MKlp2

Mitotic kinases of the Polo and Aurora families are key regulators of chromosome segregation and cytokinesis. Here, we have investigated the role of MKlp1 and MKlp2, two vertebrate mitotic kinesins essential for cytokinesis, in the spatial regulation of the Aurora B kinase. Previously, we have demon...

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Detalles Bibliográficos
Autores principales: Gruneberg, Ulrike, Neef, Rüdiger, Honda, Reiko, Nigg, Erich A., Barr, Francis A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172317/
https://www.ncbi.nlm.nih.gov/pubmed/15263015
http://dx.doi.org/10.1083/jcb.200403084