Cargando…
Relocation of Aurora B from centromeres to the central spindle at the metaphase to anaphase transition requires MKlp2
Mitotic kinases of the Polo and Aurora families are key regulators of chromosome segregation and cytokinesis. Here, we have investigated the role of MKlp1 and MKlp2, two vertebrate mitotic kinesins essential for cytokinesis, in the spatial regulation of the Aurora B kinase. Previously, we have demon...
Autores principales: | Gruneberg, Ulrike, Neef, Rüdiger, Honda, Reiko, Nigg, Erich A., Barr, Francis A. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172317/ https://www.ncbi.nlm.nih.gov/pubmed/15263015 http://dx.doi.org/10.1083/jcb.200403084 |
Ejemplares similares
-
Molecular basis of MKLP2-dependent Aurora B transport from chromatin to the anaphase central spindle
por: Serena, Michela, et al.
Publicado: (2020) -
PP1 promotes cyclin B destruction and the metaphase–anaphase transition by dephosphorylating CDC20
por: Bancroft, James, et al.
Publicado: (2020) -
Aurora B suppresses microtubule dynamics and limits central spindle size by locally activating KIF4A
por: Nunes Bastos, Ricardo, et al.
Publicado: (2013) -
The Aurora B specificity switch is required to protect from non-disjunction at the metaphase/anaphase transition
por: Kelly, Joanna R., et al.
Publicado: (2020) -
Targeting Aurora B to the Equatorial Cortex by MKlp2 Is Required for Cytokinesis
por: Kitagawa, Mayumi, et al.
Publicado: (2013)