A divergent canonical WNT-signaling pathway regulates microtubule dynamics: Dishevelled signals locally to stabilize microtubules

Dishevelled (DVL) is associated with axonal microtubules and regulates microtubule stability through the inhibition of the serine/threonine kinase, glycogen synthase kinase 3β (GSK-3β). In the canonical WNT pathway, the negative regulator Axin forms a complex with β-catenin and GSK-3β, resulting in...

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Detalles Bibliográficos
Autores principales: Ciani, Lorenza, Krylova, Olga, Smalley, Matthew J., Dale, Trevor C., Salinas, Patricia C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172322/
https://www.ncbi.nlm.nih.gov/pubmed/14734535
http://dx.doi.org/10.1083/jcb.200309096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172322/
https://www.ncbi.nlm.nih.gov/pubmed/14734535
http://dx.doi.org/10.1083/jcb.200309096

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