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FoxO3a regulates erythroid differentiation and induces BTG1, an activator of protein arginine methyl transferase 1

Erythropoiesis requires tight control of expansion, maturation, and survival of erythroid progenitors. Because activation of phosphatidylinositol-3-kinase (PI3K) is required for erythropoietin/stem cell factor–induced expansion of erythroid progenitors, we examined the role of the PI3K-controlled Fo...

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Detalles Bibliográficos
Autores principales: Bakker, Walbert J., Blázquez-Domingo, Montserrat, Kolbus, Andrea, Besooyen, Janey, Steinlein, Peter, Beug, Hartmut, Coffer, Paul J., Löwenberg, Bob, von Lindern, Marieke, van Dijk, Thamar B.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172323/
https://www.ncbi.nlm.nih.gov/pubmed/14734530
http://dx.doi.org/10.1083/jcb.200307056