Atypical protein kinase C (PKCζ/λ) is a convergent downstream target of the insulin-stimulated phosphatidylinositol 3-kinase and TC10 signaling pathways

Insulin stimulation of adipocytes resulted in the recruitment of atypical PKC (PKCζ/λ) to plasma membrane lipid raft microdomains. This redistribution of PKCζ/λ was prevented by Clostridium difficile toxin B and by cholesterol depletion, but was unaffected by inhibition of phosphatidylinositol (PI)...

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Detalles Bibliográficos
Autores principales: Kanzaki, Makoto, Mora, Silvia, Hwang, Joseph B., Saltiel, Alan R., Pessin, Jeffrey E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172328/
https://www.ncbi.nlm.nih.gov/pubmed/14734537
http://dx.doi.org/10.1083/jcb.200306152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172328/
https://www.ncbi.nlm.nih.gov/pubmed/14734537
http://dx.doi.org/10.1083/jcb.200306152

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