c-Abl phosphorylates Dok1 to promote filopodia during cell spreading

Filopodia are dynamic F-actin structures that cells use to explore their environment. c-Abl tyrosine kinase promotes filopodia during cell spreading through an unknown mechanism that does not require Cdc42 activity. Using an unbiased approach, we identified Dok1 as a specific c-Abl substrate in spre...

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Detalles Bibliográficos
Autores principales: Woodring, Pamela J., Meisenhelder, Jill, Johnson, Sam A., Zhou, Guo-Lei, Field, Jeffrey, Shah, Kavita, Bladt, Friedhelm, Pawson, Tony, Niki, Masaru, Pandolfi, Pier Paolo, Wang, Jean Y.J., Hunter, Tony
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172353/
https://www.ncbi.nlm.nih.gov/pubmed/15148308
http://dx.doi.org/10.1083/jcb.200312171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172353/
https://www.ncbi.nlm.nih.gov/pubmed/15148308
http://dx.doi.org/10.1083/jcb.200312171

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