Loss of Geminin induces rereplication in the presence of functional p53

Strict regulation of DNA replication is essential to ensure proper duplication and segregation of chromosomes during the cell cycle, as its deregulation can lead to genomic instability and cancer. Thus, eukaryotic organisms have evolved multiple mechanisms to restrict DNA replication to once per cel...

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Detalles Bibliográficos
Autores principales: Melixetian, Marina, Ballabeni, Andrea, Masiero, Laura, Gasparini, Patrizia, Zamponi, Raffaella, Bartek, Jiri, Lukas, Jiri, Helin, Kristian
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172361/
https://www.ncbi.nlm.nih.gov/pubmed/15159417
http://dx.doi.org/10.1083/jcb.200403106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172361/
https://www.ncbi.nlm.nih.gov/pubmed/15159417
http://dx.doi.org/10.1083/jcb.200403106

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