Apaf-1 and caspase-9 accelerate apoptosis, but do not determine whether factor-deprived or drug-treated cells die

Apoptosis after growth factor withdrawal or drug treatment is associated with mitochondrial cytochrome c release and activation of Apaf-1 and caspase-9. To determine whether loss of Apaf-1, caspase-2, and caspase-9 prevented death of factor-starved cells, allowing them to proliferate when growth fac...

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Detalles Bibliográficos
Autores principales: Ekert, Paul G., Read, Stuart H., Silke, John, Marsden, Vanessa S., Kaufmann, Hitto, Hawkins, Christine J., Gerl, Robert, Kumar, Sharad, Vaux, David L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172390/
https://www.ncbi.nlm.nih.gov/pubmed/15210730
http://dx.doi.org/10.1083/jcb.200312031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172390/
https://www.ncbi.nlm.nih.gov/pubmed/15210730
http://dx.doi.org/10.1083/jcb.200312031

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