Deregulation of cyclin E in human cells interferes with prereplication complex assembly

Deregulation of cyclin E expression has been associated with a broad spectrum of human malignancies. Analysis of DNA replication in cells constitutively expressing cyclin E at levels similar to those observed in a subset of tumor-derived cell lines indicates that initiation of replication and possib...

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Detalles Bibliográficos
Autores principales: Ekholm-Reed, Susanna, Méndez, Juan, Tedesco, Donato, Zetterberg, Anders, Stillman, Bruce, Reed, Steven I.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172392/
https://www.ncbi.nlm.nih.gov/pubmed/15197178
http://dx.doi.org/10.1083/jcb.200404092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172392/
https://www.ncbi.nlm.nih.gov/pubmed/15197178
http://dx.doi.org/10.1083/jcb.200404092

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