Cargando…

Plexin-B1/RhoGEF–mediated RhoA activation involves the receptor tyrosine kinase ErbB-2

Plexins are widely expressed transmembrane proteins that mediate the effects of semaphorins. The molecular mechanisms of plexin-mediated signal transduction are still rather unclear. Plexin-B1 has recently been shown to mediate activation of RhoA through a stable interaction with the Rho guanine nuc...

Descripción completa

Detalles Bibliográficos
Autores principales: Swiercz, Jakub M., Kuner, Rohini, Offermanns, Stefan
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172401/
https://www.ncbi.nlm.nih.gov/pubmed/15210733
http://dx.doi.org/10.1083/jcb.200312094