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Plexin-B1/RhoGEF–mediated RhoA activation involves the receptor tyrosine kinase ErbB-2
Plexins are widely expressed transmembrane proteins that mediate the effects of semaphorins. The molecular mechanisms of plexin-mediated signal transduction are still rather unclear. Plexin-B1 has recently been shown to mediate activation of RhoA through a stable interaction with the Rho guanine nuc...
Autores principales: | Swiercz, Jakub M., Kuner, Rohini, Offermanns, Stefan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172401/ https://www.ncbi.nlm.nih.gov/pubmed/15210733 http://dx.doi.org/10.1083/jcb.200312094 |
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